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教师简介

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金天博

个人简介

姓名:金天博
性别:男
民族:汉族
出生年月:1973年8月6日
政治面目:中共党员
学历(学位):博士
专业:药物基因组学、肿瘤遗传学、群体遗传学
联系地址:西安市太白北路229号十大赌博官方正规网站国家微检测系统工程技术研究中心
邮编:710069
Email Address:jintb@nwu.edu.cn

教育背景
1992年-1997年 西安医科大学法医学专业,获法医学学士学位。
1999年-2002年 西安交通大学赌钱平台官网法医学专业,获法医学硕士学位。
2002年-2005年 西安交通大学赌钱平台官网法医学专业,获法医学博士学位。

工作经历
1997.07-2001.03 西安医科大学法赌钱平台官网 教师、教学秘书
2001.04-2002.10 中科院北京华大基因研究中心 生物信息学主管
2002.10-2007.02 西安交通大学赌钱平台官网法医学系 教师、系主任助理
2007.02-2008.01 美国布朗大学赌钱平台官网 医学博士后
2008.02-2009.04 美国密苏里堪萨斯城市大学赌钱平台官网 生物信息学博士后
2009.04-至今 十大赌博官方正规网站国家微检测系统工程技术研究中心 主任助理
2009.12-2012.04 十大赌博官方正规网站生命科学学院 生物学博士后
2012.05-至今 十大赌博官方正规网站生命科学学院 讲师

学术任职
中国抗癌协会肿瘤标志专业委员会委员,青年委员会常委
中国生化学会医学分会青年委员
中国遗传学会会员
中国法医学会会员
陕西省肿瘤标志专业委员会常委
陕西省法医学会会员
陕西省司法鉴定协会会员
陕西省基因组与健康学会副理事长

承担的科研项目

主要基金情况
[1] 十大赌博官方正规网站西部资源生物与现代生物技术教育部重点实验室项目《CYP450家族CYP11B2基因与高原急性肺水肿的表观遗传学研究》 一项,课题编号:111110005,课题负责人;
[2] 国家自然科学基金项目 《CYP450基因家族低氧适应相关甲基化位点筛选及表观遗传学机制研究》一项,项目编号:31760312,课题负责人;
[3] 国家自然科学基金项目《大骨节病分子流行病学研究》一项,项目编号:81560516,课题负责人;
[4] 国家人社部2015年中国留学人员回国创业启动支持计划入选项目一项,课题负责人;
[5] 西安市委组织部2015年海外高层次人才引进“5211计划”一项;
[6] 国家人社部2014年度中国留学人员科技活动择优资助项目重点类一项,课题负责人;
[7] 国家人社部2013年度中国留学人员科技活动择优资助项目启动类一项,课题负责人;
[8] 国家博士后特别资助项目《脑胶质瘤个体化治疗中疗效预测分子标志物研究》一项,项目编号No. 2013T60886,课题负责人;
[9] 陕西省博士后基金项目《中国主要民族药物基因组学相关基因遗传差异研究》,2013年,课题负责人;
[10] 国家高科技发展计划(863)“重大疾病分子分型及个体化诊疗技术”子项目“个体化用药关键技术及相关产品开发”课题,课题编号2012AA02A519,课题副组长;
[11] 国家重大专项“药物代谢酶基因多态性与药物安全性和有效性关系检测技术的建立及其在新药开发中的应用”课题,课题编号2012ZX09506001-007,技术骨干;
[12] 国家博士后基金面上项目《脑胶质瘤个性化治疗中疗效预测分子标志物研究》一项,项目编号No. 2012M521798,课题负责人;
[13] 国家外专局,引进国外技术、管理人才项目:药物代谢P450酶相关试剂和药物筛选平台的产业化开发,项目编号:RJZ20116101002,课题负责人;
[14] 国家博士后特别资助项目《中国主要民族药物基因组学相关基因遗传差异研究》一项,项目编号No. 201104634,课题负责人;
[15] 国家博士后基金面上项目《中国汉族、藏族细胞色素酶(CYP450)基因遗传差异研究》一项,项目编号No. 20100471628,课题负责人;
[16] 国家高科技发展计划(863)“常见重大疾病全基因组关联分析和药物基因组学研究”子项目“开发和完善药物基因组学研究综合技术系统”课题,课题编号2009AA022710,课题副组长;
[17] 国家自然科学基金项目《I型神经纤维瘤病相关致病基因突变及其致病机理研究》,项目编号No. 81301648,协作单位负责人;
[18] 国家自然科学基金项目《RTEL1在脑胶质瘤细胞分化中的作用及机制研究》,项目编号No. 81272776,协作单位负责人;
[19] 国家自然科学基金《 “珠峰上班族”夏尔巴人和藏族高原适应机制研究》,项目编号31260252,协作单位负责人;
[20] 国家自然科学基金项目《Xq12-Xq23区域精神发育迟滞相关基因筛选与检测研究》,项目编号31100899,协作单位负责人;
[21] 陕西省省卫生厅项目《国人圆锥角膜患者VSX1基因突变位点的筛查及对可疑和隐匿型病例的预防研究》,项目编号2010D28,协作单位负责人;
[22] 陕西省科技攻关项目《基于多基因遗传回归模型的脑胶质瘤关联基因系统性研究》,项目编号No. 2012K13-01-13,协作单位负责人;
[23] 海南省社会发展科技专项项目《海南汉族、黎族细胞色素酶(CYP450)基因遗传背景差异研究》,项目编号No. SF201402,协作单位负责人;
[24] 海南省应用技术研发与示范推广专项项目《海南地区血液肿瘤靶向药物研究及个体化治疗体系的建立及应用》,项目编号No. ZDXM2014119,协作单位负责人;
[25] 陕西省科技技术攻关项目《人群遗传信息普查》一项,项目编号2005K08-G5,课题负责人;
[26] 参与国家“九五”科技攻关计划《人体硬组织DNA分型研究(1996-2000)》,项目编号No.96-919-01-04-3;
[27] 参与国家自然科学基金项目《中华民族STR遗传结构研究(1995-2000)》;
[28] 参与教育部科技基础条件创新平台项目《中华民族DNA多态性数据库检索系统建设(2004-2006)》,项目编号No.505015;
[29] 参与国家自然科学基金项目《中华民族始祖多态性位点的选择,确定与应用研究(2007-2010)》,项目编号No. 30700470;
[30] 参与国家自然科学基金项目《阿片依赖脑组织基因表达谱研究(2007-2010)》,项目编号No. 30672356;
[31] 参与国家自然科学基金项目《多巴胺受体敲除小鼠中c-Fos与FosB的表达规律研究(2007-2010)》,项目编号No. 30572089。

主要研究成果

发表论文列表
[1] Gang Ye, Nan Tan, Chenyang Meng, Jingjie Li, Li Jing, Mengdan Yan, Tianbo Jin, and Fulin Chen. Genetic variations in TERC and TERT genes are associated with lung cancer risk in a Chinese Han population[J]. Oncotarget, 2017, 8(66): 110145. IF 5.168
[2] Yanbin Song, Mengdan Yan, Jing Li, Jingjie Li, Tianbo Jin, and Chao Chen. Association between TNIP1, MPHOSPH6 and ZNF208 genetic polymorphisms and the coronary artery disease risk in Chinese Han population[J]. Oncotarget, 2017, 8(44): 77233. IF 5.168
[3] Tianbo Jin, Wei Cao, Xiaoxiao Zuo, Miao Li, Ya Yang, Tiansong Liang, Hongyao Yang, Xinhan Zhao, Daoke Yang. IL‐1RN gene polymorphisms are associated with breast cancer risk in a Chinese Han population[J]. J Gene Med, 2017, 19(12). IF 2.524
[4] Jianzhong Wang, Xugang Shi, Hua Yang, Jieli Du, Yongri Ouyang, Hong Wang, Tianbo Jin, and Chao Chen. Association between alcohol-induced osteonecrosis of femoral head and risk variants of MMPS in Han population based on a case-control study[J]. Oncotarget, 2017, 8(38): 64490. IF 5.168
[5] Mengdan Yan, Jingjie Li, Na He,Xugang Shi, Shuli Du, Bin Li, Tianbo Jin. A case-control study of the association between the EGFR gene and glioma risk in a Chinese Han population[J]. Oncotarget, 2017, 8(35): 59823. IF 5.168
[6] Fanglin Niu, Jingjie Li, Jing Li, Mengdan Yan, Xugang Shi, Tianbo Jin. Polymorphisms of telomere-length related genes in three China ethnic groups [J]. Int J Clin Exp Pathol, 2017, 10(9): 9654-9665. IF 1.581
[7] Yuqiang Ji, Yanbin Song, Qingwen Wang, Pengcheng Xu, Zhao Zhao, Xia Li, Nan Wang, Tianbo Jin, and Chao Chen. Sex-specific association of SH2B3 and SMARCA4 polymorphisms with coronary artery disease susceptibility [J]. Oncotarget, 2017, 8(35): 59397. IF 5.168
[8] Bin Li, Yang Li, Mengdan Yan, Jing Li, Jingjie Li, Shuli Du, Tianbo Jin, Yongkuan Gong. Association of NFIL3, XRCC5 polymorphisms with glioblastoma in Han Chinese population [J]. Int J Clin Exp Pathol, 2017, 10(4): 4838-4846. IF 1.581
[9] Yifei Wu, Mengdan Yan, Jing Li, Jingjie Li, Zhengshuai Chen, Peng Chen, Bin Li, Fulin Chen, Tianbo Jin and Chao Chen. Genetic polymorphisms in TERT are associated with increased risk of esophageal cancer [J]. Oncotarget, 2017, 8(6): 10523. IF 5.008
[10] Jing Li, Jiache Wei, Pengcheng Xu, Mengdan Yan, Jingjie Li, Zhengshuai Chen, and Tianbo Jin. Impact of diabetes-related gene polymorphisms on the clinical characteristics of type 2 diabetes Chinese Han population[J]. Oncotarget, 2016, 7(51): 85464. IF 5.008
[11] Peng Chen, Zhengshuai Chen, Jinglie Li, Hua Yang, Yuanyuan Zhu, Ning Zhang, Mengdan Yan, Yuan Shao, Chao Chen and Tianbo Jin. Gene polymorphisms are associated with clinical outcome in Chinese resected laryngeal carcinoma patients [J]. Oncotarget, 2016, 7(44): 71703-71709. IF 5.008
[12] Ming Liu, Bin Li, Wen Guo, Xiyang Zhang, Zhengshuai Chen, Jingjie Li, Mengdan Yan, Chao Chen and Tianbo Jin. Association between single nucleotide polymorphisms in the TSPYL6 gene and breast cancer susceptibility in the Han Chinese population [J]. Oncotarget, 2016, 7(34): 54771. IF 5.008
[13] Bin Li, Wenhui Zhao, Jingjie Li, Mengdan Yan, Zhilan Xie, Yuanyuan Zhu, Chao Chen and Tianbo Jin. Effect of epidermal growth factor receptor gene polymorphisms on prognosis in glioma patients [J]. Oncotarget, 2016, 7(39): 63054. IF 5.008
[14] Ying Sun, Yi Yuan, Hua Yang, Jingjie Li, Tian Feng, Yongri Ouyang, Tianbo Jin, and Ming Liu. Association between Common Genetic Variants and Polycystic Ovary Syndrome Risk in a Chinese Han Population[J]. J Clin Res Pediatr E, 2016, 8(4): 405. IF 1.118
[15] Jingjie Li, Zhengshuai Chen, Fengjiao Wang, Yongri Ouyang, Ning Zhang, Min Yang, Mengdan Yan, Xikai Zhu, Xue He, Dongya Yuan and Tianbo Jin. Polymorphisms of the TCF4 gene are associated with the risk of schizophrenia in the Han Chinese [J]. Am J Med Genet B, 2016. 171(8): 1006-1012. IF 3.391
[16] Huijuan Wang, Hua Yang, Tian Feng, Tingting Geng, Chao Chen, Tianbo Jin. Effects of TERT gene polymorphism and environmental factor interactions on lung cancer risk in the Xi’an Han population [J]. Int J Clin Exp Med, 2016, 9(2): 4200-4210. IF 1.075
[17] Yongchao Ren, Tianbo Jin, Xiaodian Sun, Tingting Geng, Mingxia Zhang, Li Wang, Tian Feng, Longli Kang and Chao Chen. PDK2 and ABCG2 genes polymorphisms are correlated with blood glucose levels and uric acid in Tibetan gout patients [J]. Genet Mol Res, 2016, 15(1). IF 0.764
[18] Zhengshuai Chen, Jingjie Li, Peng Chen, Fengjiao Wang, Ning Zhang, Min Yang, Tianbo Jin, Chao Chen. Genetic polymorphisms of the drug-metabolizing enzyme cytochrome P450 3A5 in a Uyghur Chinese population [J]. Xenobiotica, 2016: 1-7. IF 2.199
[19] Tianbo Jin, Mingxia Zhang, Hua Yang, Tingting Geng, Ning Zhang, Tian Feng, Yajuan Ma, Dongya Yuan and Longli Kang. Genetic polymorphisms of the drug-metabolizing enzyme CYP2C19 in the Uyghur population in northwest China [J]. Xenobiotica, 2016, 46(7): 634-640. IF 2.199
[20] Tingting Geng, Xi yang Zhang, Li Wang, Huijuan Wang, Xugang Shi, Longli Kang, Peng Hou, Tianbo Jin. Genetic polymorphism analysis of the drug-metabolizing enzyme CYP1A2 in a Uyghur Chinese population: A pilot study[J]. Xenobiotica, 2016, 46(6): 542-547. IF 2.199
[21] Long Zhou, Na He, Tian Feng, Tingting Geng, Tianbo Jin, Chao Chen. Association of five single nucleotide polymorphisms at 6q25. 1 with breast cancer risk in northwestern China [J]. Am J Cancer Res 2015, 5(8):2467-2475. IF 4.165
[22] Tianbo Jin, Yuan Wang, Gang Li, Shuli Du, Hua Yang, Tingting Geng, Peng Hou, Yongkuan Gong. Analysis of difference of association between polymorphisms in the XRCC5, RPA3 and RTEL1 genes and glioma, astrocytoma and glioblastoma [J]. Am J Cancer Res 2015;5(7):2294-2300 IF 4.165
[23] Xiyang Zhang, Tingting Geng, Lijun Liu, Dongya Yuan, Tian Feng, Longli Kang, Tianbo Jin, Chao Chen. SLC2A9 and ZNF518B polymorphisms correlate with gout-related metabolic indices in Chinese Tibetan populations [J]. Genet Mol Res, 2015, 14(3): 9915-9921. IF 0.764
[24] Tianbo Jin, Hua Yang, Jiayi Zhang, Zulfiya Yunus, Qiang Sun, Tingting Geng, Chao Chen, Jie Yang. Polymorphisms and phenotypic analysis of cytochrome P450 3A4 in the Uygur population in northwest China [J]. Int J Clin Exp Pathol, 2015, 8(6): 7083. IF 1.581
[25] Wenjing Zhou, Tingting Geng, Huijuan Wang, Xiaojie Xun, Tian Feng, Hui Zou, Longli Kang, Tianbo Jin, Chao Chen. CHRNA3 genetic polymorphism and the risk of lung cancer in the Chinese Han smoking population [J]. Tumor Biol, 2015: 1-6. IF 2.926
[26] Le Zhang, Tianbo Jin, Ya Gao, Huijuan Wang, Hua Yang, Tian Feng, Chen Chen, Longli Kang, Chao Chen. Meta-Analysis of the Association between the rs8034191 Polymorphism in AGPHD1 and Lung Cancer Risk [J]. Asian Pac J Cancer P, 2015, 16(7): 2713-2717. IF 2.514
[27] Shuli Du, Tingting Geng, Tian Feng, Cuiping Chen, Tianbo Jin, Chao Chen. The RTEL1 rs6010620 Polymorphism and Glioma Risk: a Meta-analysis Based on 12 Case-control Studies [J]. Asian Pac J Cancer P, 2014, 15(23): 10175. IF 2.514
[28] Jiayi Zhang, Tianbo Jin, Zulfiya Yunus, Xiaolan Li, Tingting Geng, Hong Wang, Yali Cui and Chao Chen. Genetic polymorphisms of VIP variants in the Tajik ethnic group of northwest China [J]. BMC Genet, 2014, 15(1): 102. IF 2.397
[29] Xiaojie Xun, Huijuan Wang, Hua Yang, Hong Wang, Bo Wang, Longli Kang, Tianbo Jin and Chao Chen. CLPTM1L Genetic Polymorphisms and Interaction With Smoking and Alcohol Drinking in Lung Cancer Risk: A Case–Control Study in the Han Population From Northwest China [J]. Medicine, 2014, 93(28): e289. IF 5.723
[30] Huijuan Wang, Ting Bian, Tianbo Jin, Yong Chen, Aifen Lin, Chao Chen. Association analysis of UGT1A genotype and haplotype with SN-38 glucuronidation in human livers [J]. Pharmacogenomics, 2014, 15(6): 785-798. IF 2.71
[31] Hua Yang, Ya Gao, Tian Feng, Tianbo Jin, Longli Kang, Chao Chen. Meta-Analysis of the rs4779584 Polymorphism and Colorectal Cancer Risk [J]. PloS one, 2014, 9(2): e89736. IF 3.234
[32] Xianglong Duan, Xiaolan Li, Huiling Lou, Tingting Geng, Tianbo Jin, Ping Liang, Shanqu Li, Yanbin Long, Chao Chen. Genetic association of PLCE1, C11orf92-C11orf93, and NOC3L with colorectal cancer risk in the Han population [J]. Tumor Biol, 2014, 35(3): 1813-1817. IF 3.611
[33] Peng Xia, Tianbo Jin, Tingting Geng, Ting Sun, Xiaolan Li, Chengxue Dang, Longli Kang, Chao Chen, Jiying Sun. Polymorphisms in ESR1 and FLJ43663 are associated with breast cancer risk in the Han population [J]. Tumor Biol, 2014, 35(3): 2187-2190. IF 3.611
[34] Zulfiya Yunus, Lijun Liud, HongWang, Le Zhang, Xiaolan Li, Tingting Geng, Longli Kang, Tianbo Jin, Chao Chena. Genetic polymorphisms of pharmacogenomic VIP variants in the Kyrgyz population from northwest China [J]. Gene, 2013, 529(1): 88-93. IF 2.082
[35] Tianbo Jin, Jiayi Zhang, Gang Li, Shuli Du, Tingting Geng, Jing Gao, Qianping Liu, Guodong Gao, Longli Kang, Chao Chen, Shanqu Li. RTEL1 and TERT polymorphisms are associated with astrocytoma risk in the Chinese Han population [J]. Tumor Biol, 2013: 1-8. IF 3.611
[36] Tianbo Jin, Xiaolan Li, Jiayi Zhang, Hong Wang, Tingting Geng, Gang Li, Guodong Gao and Chao Chen. Genetic association between selected cytokine genes and glioblastoma in the Han Chinese population [J]. BMC Cancer, 2013, 13(1): 236. IF 3.319
[37] Tianbo Jin, Jiayi Zhang, Gang Li, Shanqu Li, Bo Yang, Chao Chen, and Linbo Cai. TP53 and RPA3 Gene Variations Were Associated with Risk of Glioma in a Chinese Han Population [J]. Cancer Biother Radi, 2013, 28(3): 248-253. IF 1.715
[38] Tianbo Jin, Gang Li, Dong Lin, Hongjuan Liang, Qing Wang. A single nucleotide polymorphism (SNP) assay for population stratification test between eastern Asians in association studies [J]. Afr J Biotechnol, 2012, 11(1): 1-36.
[39] Huijuan Wang, Ting Bian, Duan Liu, Tianbo Jin, Yong Chen, Aifen Lin, Chao Chen. Association analysis of CYP2A6 genotypes and haplotypes with 5-fluorouracil formation from tegafur in human liver microsomes [J]. Pharmacogenomics, 2011, 12(4): 481-492. IF 2.71
[40] Tianbo Jin, Jiahan Li, Ying Guo, Xiaojing Zhou, Runqing Yang, Rongling Wu. An optimal strategy for functional mapping of dynamic trait loci [J]. Genet Res, 2010, 92(1): 55-62. IF 0.743

获得的教学和科研表彰

奖励情况(省级以上)
陕西省现代教育技术成果二等奖一项
陕西省高等学校科技进步三等奖一项
陕西省高等学校科技进步二等奖一项

金天博

所属部门: 教师
职称:讲师
荣誉: 硕士生导师
研究方向:
电子邮件: jintb@nwu.edu.cn